LncVar
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About
Human-CNVs :
Copy Number Variation (CNV) is a form of structural variation.
CNVs might result in deletion or amplification of large regions of the genome. The expression levels of genes located in CNV regions might be affected. We obtained CNV regions of 30 cancers from TCGA Copy Number Portal at Broad Institute, and found lncRNA genes located in these regions. We got expression levels of lncRNAs and clinical data of patiens from TCGA and performed survival analysis.
We identified lncRNAs as prognostic biomarker candidates and plotted Kaplan-Meier curves for these candidates.
Schematic overview of identifying lncRNAs in CNV regions as prognostic biomarker candidates:
CNV ID
Chr
Start
End
Type
LncRNA Number
Sample Number
Disease
CNV ID
Chr
Start
End
Type
LncRNA Number
Sample Number
Disease